Abstract
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and dysregulation of glucose metabolism. Emerging evidence suggests that alterations in gut microbiota composition may play a role in the pathogenesis of T2DM. Probiotics, live microorganisms that confer health benefits when consumed in adequate amounts, have been proposed as a potential therapeutic strategy for improving gut microbiota composition and metabolic health in individuals with T2DM. However, the effects of probiotic supplementation on gut microbiota and metabolic parameters in adults with T2DM remain unclear. This randomized controlled trial will provide valuable insights into the potential effects of probiotic supplementation on gut microbiota composition and metabolic health in adults with T2DM. The findings may have implications for the development of adjunctive therapies targeting the gut microbiota in the management of T2DM. Further research is warranted to elucidate the underlying mechanisms and optimize probiotic interventions for individuals with T2DM.
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